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Jordan Henderson appears unlikely to recover from a foot injury in time to face Arsenal, while Dejan Lovren is still a doubt due to a knee problem although he has returned to training.
Ragnar Klavan may be the only alternative to Lucas Leiva in central defence alongside Joel Matip, then, with Nathaniel Clyne and James Milner set to keep their places in the full-back positions.
Emre Can, Georginio Wijnaldum and Adam Lallana are all likely starters in central midfield in the expected absence of Henderson, while the front three of Sadio Mane, Roberto Firmino and Philippe Coutinho is also set to remain unchanged.
Divock Origi may be the main alternative in attack if Daniel Sturridge remains out due to illness.
Ovie Ejaria and Marko Grujic are still doubtful, while Danny Ings is a long-term absentee for the Reds.
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