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Theo Walcott (calf) and Hector Bellerin (ankle) remain sidelined for the trip to south Wales but Mesut Ozil (illness) has been passed fit.
Gabriel is likely to be stationed at right-back, then, with Shkodran Mustafi and Laurent Koscielny in central defence. Kieran Gibbs – if he recovers from a knee problem – is perhaps a viable alternative to Nacho Monreal at left-back.
Granit Xhaka and Aaron Ramsey look set to continue at the base of midfield in the 4-2-3-1, with Alex Iwobi, Ozil and Alexis Sanchez perhaps forming the attacking midfield trio. Alex Oxlade-Chamberlain and Lucas Perez may push Iwobi for a starting spot, though.
The in-form Olivier Giroud could lead the line once again, unless Arsene Wenger favours the pace of Sanchez in the lone striker role, which would allow one of either Oxlade-Chamberlain or Perez to earn a start out wide.
Per Mertesacker, Mathieu Debuchy, Francis Coquelin and Santi Cazorla remain sidelined, while Mohamed Elneny is unavailable due to his participation in the Africa Cup of Nations.
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